
赵冬菊,博士,2023年6月毕业于天津大学,yl23455永利讲师。
主讲课程
本科生:《药物分析》、《药物分析与实验》、《新生研讨课(生物医药)》
研究生:《小分子药物制备技术》
科研领域及方向
[1] 基于天然分子的多功能水凝胶的制备与应用
[2] 智能药物/蛋白质递送系统的设计与应用
主要学术成果
先后发表各类科研论文11篇,申请/授权国家发明专利5项。
发表的主要学术论文有:
[1] Dongju Zhao#, Fan Yang#, Yining Liu, Meng Cheng, Ziyao Chen, Caihua Ye, Jin Chang*, Yan Dou *. Cross-scale targeted remodeling of neurovascular and neurometabolic coupling in Alzheimer’s disease by natural self-assembled SIRT1 activator. Nano Today, 2024, 57, 102340. (IF=10.9,二区TOP)
[2] Dongju Zhao#, Chao Tian#, Meng Cheng, Fan Yang, Chunxiao Tian, Yining Liu, Ziyao Chen, Gaoju Pang, Hui Shen*, Jin Chang*, Yan Dou*. Carrier-free quercetin nanomedicine blocks NLRP3 deubiquitination and TXNIP recruitment for Parkinson’s disease therapy. Chemical Engineering Journal, 2023, 464, 142697. (IF=13.2,一区TOP)
[3] Dongju Zhao, Yuqing Tang, Xinjun Suo, Chaonan Zhang, Yan Dou*, Jin Chang*. A dual-targeted multifunctional nanoformulation for potential prevention and therapy of Alzheimer’s disease. Innovation, 2021, 2, 100160. (IF=25.7,一区TOP)
[4] Yining Liu#, Dongju Zhao#, Fan Yang, Caihua Ye, Ziyao Chen, Yihan Chen, Xiaomeng Yu, Jiyao Xie, Yan Dou,* and Jin Chang*. In situ self-assembled phytopolyphenol coordinated intelligent nanotherapeutics for multipronged management of ferroptosis driven Alzheimer’s disease. ACS Nano, 2024, 18, 7890-7906. (IF=16.0,一区TOP)
[5] Ziyao Chen#, Dongju Zhao#, Meng Cheng, Fan Yang, Yining Liu, Jin Chang*, Yan Dou*. Female-sensitive multifunctional phytoestrogen nanotherapeutics for tailored management of postmenopausal Alzheimer’s disease. Nano Today, 2024, 54, 102119. (IF=10.9,二区TOP)
[6] Yan Dou#,*, Dongju Zhao#, Fan Yang, Yuqing Tang, Jin Chang*. Natural phyto-antioxidant albumin nanoagents to treat advanced Alzheimer’s disease. ACS Applied Materials & Interfaces, 2021, 13(26), 30373-30382. (IF=8.2,二区)
[7] Yan Dou#,*, Dongju Zhao#. Targeting emerging pathogenic mechanisms by natural molecules as potential therapeutics for neurodegenerative diseases. Pharmaceutics, 2022, 14(11), 2287. (IF=5.5,三区)
申请/授权发明专利主要有:
[1] 一种温敏水凝胶及其制备方法与应用. 中国发明专利公开号:CN120678719A.
[2] 一种靶向Aβ老年斑的普鲁士蓝纳米颗粒及其制备方法. 中国发明专利授权号:ZL201910217120X.
[3] 普鲁士蓝纳米颗粒在制备预防、延缓或治疗神经系统退行性疾病药物中的应用. 中国发明专利授权号:ZL2020105190120.
[4] PPLICATION OF PRUSSIAN BLUE NANOPARTICLES IN PREPARATION OF DRUG FOR PREVENTING, DELAYING OR TREATING NERVOUS SYSTEM DEGENERATIVE DISEASE. PCT国际公布号:WO/2021/218004.
联系方式
办公地点:天津经济技术开发区第十三大街29号yl23455永利
邮政编码:300457
Email: zhaodongju@tust.edu.cn